Rivaroxaban (S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Rivaroxaban (S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Ti a lo ninu awọn alaisan agbalagba ti o ni ibadi yiyan tabi iṣẹ abẹ rirọpo orokun lati ṣe idiwọ iṣọn-ẹjẹ iṣọn-ẹjẹ (VTE).
O ti wa ni lo lati se tabi din awọn Ibiyi ti thrombosis, jin iṣọn thrombosis (DVT) ati ẹdọforo embolism (PE) lẹhin ibadi tabi orokun rirọpo abẹ.
Iwọn ti a ṣe iṣeduro jẹ rivaroxaban oral 10mg, lẹẹkan ni ọjọ kan.Rivaroxaban 10mg le ṣee mu pẹlu ounjẹ tabi nikan.Rivaroxaban 15mg tabi awọn tabulẹti 20mg yẹ ki o mu pẹlu ounjẹ.
bošewa: usp40
Ayẹwo: 99-102%
Òde: White lulú
Package: 25kg / ilu
Mu 4- (4-aminophenyl) morpholin-3-ọkan (SM-1), (S) -N-glycidyl phthalimide (SM-2), 5-chlorothiophene-2- Formyl chloride (SM-3) jẹ ohun elo ibẹrẹ .Lẹhin ti condensation, cyclization, aminolysis ati acylation, awọn robi rivaroxaban ti wa ni gba, ati awọn ti pari rivaroxaban ti wa ni refaini.
Igbaradi: Ọja yii jẹ tabulẹti ti a bo fiimu pupa.
Awọn ẹya ara ẹrọ:
Ohun elo tabulẹti: microcrystalline cellulose, iṣuu soda croscarmellose, lactose monohydrate, hypromellose, iṣuu soda lauryl sulfate, iṣuu magnẹsia stearate.
Aso: polyethylene glycol, hypromellose, titanium oloro, irin oxide pupa
Rivaroxaban jẹ yiyan giga, oogun ẹnu ti o ṣe idiwọ ifosiwewe Xa taara.Nipasẹ yiyan ti o ga julọ ati idije idije ti ominira ati ifunmọ ifosiwewe Xa ati iṣẹ-ṣiṣe prothrombin, fa fifalẹ apakan ti akoko thromboplastin ti a mu ṣiṣẹ (PT) ati akoko prothrombin (aPTT) ni ọna ti o gbẹkẹle iwọn lilo, eyiti o le da gbigbi isosile omi coagulation Awọn ipa ọna ailopin ati exogenous ṣe idiwọ iṣelọpọ ti thrombin ati thrombosis.Rivaroxaban ko ṣe idiwọ thrombin (ipin mimu ṣiṣẹ Ⅱ), tabi ti fihan pe o ni ipa lori awọn platelets.
Iyatọ ti o ṣe pataki laarin rivaroxaban ati fondaparinux/heparin ni pe ko nilo ikopa ti antithrombin III ati pe o le tako taara free ati ifosiwewe Xa;nigba ti heparin nilo antithrombin III lati ṣiṣẹ, ati pe Ko ni ipa lori ifosiwewe Xa ni eka prothrombin.
JIN DUN Medical niIjẹrisi ISO ati pade awọn iṣedede iṣelọpọ GMP, oojọ ti abele ati ajeji oogun kolaginni amoye pẹlu ọlọrọ iriri lati dari R&D ile-iṣẹ.
TECHNOL OGY anfani
● Giga titẹ agbara ti o ni itọsi hydrogenation.Iṣeduro Hydrogenolysis Ipa giga.Idahun Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
● Iṣe atunṣe
● Ipinnu Chiral
●Hekki, Suzuki,Negishi,Sonogashira .Gignard lenu
Awọn ohun elo
Lab wa ni orisirisi awọn ohun elo idanwo ati awọn ohun elo idanwo, gẹgẹbi: NMR (Bruker 400M), HPLC, Chiral-HPLC, LC-MS, LC-MS/MS (API 4000) Makirowefu Synthesizer, Parallel Synthesizer, Iyatọ Ṣiṣayẹwo Calorimeter (DSC), Maikirosikopu Electron...
R&D Egbe
Jindun Medical ni ẹgbẹ kan ti oṣiṣẹ R&D alamọdaju, o si gba ọpọlọpọ awọn amoye iṣelọpọ oogun ti ile ati ajeji lati ṣe itọsọna R&D, ṣiṣe iṣelọpọ wa ni deede ati daradara.
A ti ṣe iranlọwọ fun ọpọlọpọ awọn ile-iṣẹ elegbogi inu ile, biiHansoh, Hengrui ati HEC Pharm.Nibi a yoo ṣe afihan apakan ninu wọn.
Ọran Isọdi Ọkan:
Cas No.: 110351-94-5
Isọdi Isọdi Meji:
Cas No.: 144848-24-8
Ọran Isọdọtun Mẹta:
Cas No.: 200636-54-0
1.Ṣe akanṣe Awọn agbedemeji Tuntun tabi APIs.Kanna gẹgẹbi pinpin ọran loke, awọn alabara ni awọn ibeere fun Awọn agbedemeji kan pato tabi awọn API, ati pe wọn ko le rii awọn ọja ti o nilo ni ọja, lẹhinna a le ṣe iranlọwọ lati Ṣe akanṣe.
2.Imudara ilana fun Awọn ọja atijọ.Ẹgbẹ wa yoo ṣe iranlọwọ lati mu ki o mu iru iṣelọpọ pọ si ti ipa ọna iṣe rẹ jẹ arugbo, idiyele iṣelọpọ ga, ati ṣiṣe jẹ kekere.A le pese iwe kikun fun gbigbe imọ-ẹrọ ati ilọsiwaju ilana, iranlọwọ alabara fun iṣelọpọ ti o munadoko diẹ sii.
Lati awọn ibi-afẹde oogun si awọn IND, Iṣoogun JIN DUN pese fun ọawọn solusan R&D ti ara ẹni iduro-ọkan.
Iṣoogun JIN DUN tẹnumọ lori ṣiṣẹda ẹgbẹ kan pẹlu awọn ala, ṣiṣe awọn ọja ti o ni ọlá, titọ, lile, ati lilọ gbogbo jade lati jẹ alabaṣepọ ti o gbẹkẹle ati ọrẹ awọn alabara!
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