Guanosin
Guanosin
Guanosine ti lo bi agbedemeji Valaciclovir.
Valacyclovir jẹ oogun ajẹsara afọwọṣe guanine kan.O ti wa ni lo ninu awọn isẹgun itọju ti Herpes simplex ati Herpes zoster ikolu ni ibalopọ zqwq arun.Ọja yii jẹ iṣaju ti acyclovir.O gba ni kiakia lẹhin iṣakoso ẹnu ati ni kiakia yipada si acyclovir ninu ara.Ipa antiviral rẹ jẹ ṣiṣẹ nipasẹ acyclovir.Lẹhin ti acyclovir ti wọ inu awọn sẹẹli ti o ni arun Herpes, o dije pẹlu deoxynucleoside fun ọlọjẹ thymidine deoxynucleoside kinase tabi cell kinase, ati pe oogun naa jẹ phosphorylated sinu acyclic guanosine triphosphate ti a mu ṣiṣẹ.Gẹgẹbi sobusitireti ti ẹda ọlọjẹ, acyclovir dije pẹlu deoxyguanine triphosphate fun ọlọjẹ DNA polymerase, eyiti o ṣe idiwọ iṣelọpọ DNA ọlọjẹ ati ṣafihan ipa antiviral.Iṣẹ-ṣiṣe antiviral ti ọja yii ni vivo dara ju acyclovir, ati atọka itọju ti Herpes simplex virus type I ati iru II jẹ 42.91% ati 30.13% ga ju acyclovir lọ ni atele.O tun ni ipa itọju giga lori ọlọjẹ varicella zoster.
JIN DUN Medical niIjẹrisi ISO ati pade awọn iṣedede iṣelọpọ GMP, oojọ ti abele ati ajeji oogun kolaginni amoye pẹlu ọlọrọ iriri lati dari R&D ile-iṣẹ.
TECHNOL OGY anfani
● Giga titẹ agbara ti o ni itọsi hydrogenation.Iṣeduro Hydrogenolysis Ipa giga.Idahun Cryogenic (<-78%C)
●Aromatic Heterocyclic Synthesis
● Iṣe atunṣe
● Ipinnu Chiral
●Hekki, Suzuki,Negishi,Sonogashira .Gignard lenu
Awọn ohun elo
Lab wa ni orisirisi awọn ohun elo idanwo ati awọn ohun elo idanwo, gẹgẹbi: NMR (Bruker 400M), HPLC, Chiral-HPLC, LC-MS, LC-MS/MS (API 4000) Makirowefu Synthesizer, Parallel Synthesizer, Iyatọ Ṣiṣayẹwo Calorimeter (DSC), Maikirosikopu Electron...
R&D Egbe
Jindun Medical ni ẹgbẹ kan ti oṣiṣẹ R&D alamọdaju, o si gba ọpọlọpọ awọn amoye iṣelọpọ oogun ti ile ati ajeji lati ṣe itọsọna R&D, ṣiṣe iṣelọpọ wa ni deede ati daradara.
A ti ṣe iranlọwọ fun ọpọlọpọ awọn ile-iṣẹ elegbogi inu ile, biiHansoh, Hengrui ati HEC Pharm.Nibi a yoo ṣe afihan apakan ninu wọn.
Ọran Isọdi Ọkan:
Cas No.: 110351-94-5
Isọdi Isọdi Meji:
Cas No.: 144848-24-8
Ọran Isọdọtun Mẹta:
Cas No.: 200636-54-0
1.Ṣe akanṣe Awọn agbedemeji Tuntun tabi APIs.Kanna gẹgẹbi pinpin ọran loke, awọn alabara ni awọn ibeere fun Awọn agbedemeji kan pato tabi awọn API, ati pe wọn ko le rii awọn ọja ti o nilo ni ọja, lẹhinna a le ṣe iranlọwọ lati Ṣe akanṣe.
2.Imudara ilana fun Awọn ọja atijọ.Ẹgbẹ wa yoo ṣe iranlọwọ lati mu ki o mu iru iṣelọpọ pọ si ti ipa ọna iṣe rẹ jẹ arugbo, idiyele iṣelọpọ ga, ati ṣiṣe jẹ kekere.A le pese iwe kikun fun gbigbe imọ-ẹrọ ati ilọsiwaju ilana, iranlọwọ alabara fun iṣelọpọ ti o munadoko diẹ sii.
Lati awọn ibi-afẹde oogun si awọn IND, Iṣoogun JIN DUN pese fun ọawọn solusan R&D ti ara ẹni iduro-ọkan.
Iṣoogun JIN DUN tẹnumọ lori ṣiṣẹda ẹgbẹ kan pẹlu awọn ala, ṣiṣe awọn ọja ti o ni ọlá, titọ, lile, ati lilọ gbogbo jade lati jẹ alabaṣepọ ti o gbẹkẹle ati ọrẹ awọn alabara!
