5- [2-cyclopropyl-1- (2-fluorophenyl) -2-oxoethyl] - 5,6,7,7a-tetrahydrothieno [3,2-c] pyridin-2 (4h) -ọkan

5-[2-cyclopropyl-1- (2-fluorophenyl) -2-oxoethyl] - 5,6,7,7a-tetrahydrothieno [3,2-c] pyridin-2 (4h) -ọkan ni a lo bi agbedemeji ti Prasugrel.
Prasugrel jẹ thiophenopyridine antiplatelet ti o ni idagbasoke nipasẹ Eli Lilly ati daiichisankyo, olupese elegbogi Japanese kan.O jẹ oogun iṣaaju.O ṣe agbekalẹ moleku ti nṣiṣe lọwọ lẹhin iṣelọpọ nipasẹ cytochrome P450 ninu ẹdọ ati pe o dapọ pẹlu olugba platelet P2Y12 lati ṣiṣẹ lọwọ lodi si ikojọpọ platelet.Awọn ijinlẹ ile-iwosan ti fihan pe iwọn lilo 60 miligiramu ni ipa anticoagulant ti o dara julọ ju iwọn lilo iwọn miligiramu 300 ati iwọn lilo 600 miligiramu ti o pọ si ti clopidogrel, eyiti o le dinku eewu okeerẹ ti ikọlu ọkan, ọpọlọ ati iku nitori arun ọkan nipasẹ 20%, ati pe o ni ipa iyara. , ti o dara alumoni ipa, ti o dara oògùn resistance ati bioavailability, ati kekere majele ti.